Background：nm23-H7, also known as NME7 （non-metastatic cells 7）, is a 376 amino acid protein that contains one DM10 domain and belongs to the NDK family. Using magnesium as a cofactor, nm23-H7 functions to catalyze the ATP-dependent creation of nucleoside triphosphates, thereby playing an essential role in metabolic pathways throughout the body. The gene encoding nm23-H7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8％ of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
仕様
Synonyms：MN23H7,NDK 7,NDK7,NDP kinase 7,nm23 H7,nm23-H7,NME/NM23 family member 7,Nme7,Non metastatic cells 7 protein expressed in （nucleoside diphosphate kinase）,Nucleoside diphosphate kinase 7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human NME7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q9Y5B8
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
