Background：This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signaling cascade common to receptors of the tumour-necrosis/nerve-growth factor （TNF/NGF） family and to the interleukin-1 type-I receptor.
仕様
Synonyms：MAP3K14,FTDCR1B,HS,HsNIK,M3K14,Map3k14,Mitogen activated protein kinase kinase kinase 14,Mitogen-activated protein kinase kinase kinase 14,NF kappa beta inducing kinase,NF-kappa-beta-inducing kinase,NIK,Serine/threonine-protein kinase NIK
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human MAP3K14
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q99558
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
