Background:This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:59 kDa serine/threonine protein kinase,59 kDa serine/threonine-protein kinase,DKFZp686F1765,Epididymis secretory protein Li 28,HEL S 28,ILK 1,ILK 2,ILK,ILK-1,ILK-2,ILK,ILK1,ILK2,Integrin linked kinase 2,Integrin linked Kinase,Integrin linked protein kinase,Integrin-linked protein kinase,p59,p59ILK
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human ILK
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3