Background：Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones （H2A, H2B, H3, and H4） form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
仕様
Synonyms：H1 histone family member 2,H1.a,H12,H1F2,H1s-1,HIST1H1C,Histone 1 H1c,Histone cluster 1 H1c,Histone H1.2,Histone H1c,Histone H1d,Histone H1s-1,MGC3992
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human HIST1H1C
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：100-1：300
Swissprot：P16403
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
