Background：The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements （AREs） found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
仕様
Synonyms：ELAV （embryonic lethal abnormal vision Drosophila） like 1,ELAV （embryonic lethal,abnormal vision,Drosophila） like 1 （Hu antigen R）,ELAV like 1,ELAV like RNA binding protein 1,ELAV-like protein 1,ELAV1,ELAV1,Elavl1,Embryonic lethal abnormal vision drosophila homolog like 1,Hu Antigen R,Hu-antigen R,Hua,HuR,MelG
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Recombinant protein of human ELAVL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q15717
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
