Background:EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).
仕様
Synonyms:AT225,Early growth response 1,Early growth response protein 1,EGR 1,EGR-1,EGR1,EGR1,G0S30,KROX 24,KROX24,Nerve growth factor-induced clone A,Nerve growth factor-induced protein A,NGFI-A,NGFIA,TIS8,Transcription factor ETR103,Transcription factor Zif268,ZIF 268,ZIF268,Zinc finger protein 225,Zinc finger protein Krox-24,ZNF225
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.1mg/mL
Immunogen:Recombinant protein of human EGR1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P18146
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling