Background:This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
仕様
Synonyms:Dickkopf 2,Dickkopf gene 2 ,Dickkopf homolog 2,Dickkopf related protein 2,Dickkopf WNT signaling pathway inhibitor 2,Dickkopf-2,Dickkopf-related protein 2,Dickkopf2,DKK 2,Dkk-2,Dkk2,DKK2,hDkk 2,hDkk-2,hDkk2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Recombinant protein of human DKK2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3