Background:This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity.
仕様
Synonyms:Adipocyte differentiation inhibitor protein,Brevideltin,Delta like 1 homolog,Delta like homolog,Delta like protein,Delta1,DLK 1,DLK,DLK-1,DLK1,DLK1,FA 1,FA1,Fetal antigen 1,pG2,Preadipocyte factor 1,Pref 1,Pref,Pref1,Protein delta homolog 1,Secredeltin,ZOG
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human DLK1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P80370
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells