Background:CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
仕様
Synonyms:C3orf4,Chromosome 3 open reading frame 4,Claudin domain containing 1,Claudin domain containing 1 protein,GENX 3745,Membrane protein GENX3745,MGC111162,MGC3316,MGC9861,OTTHUMP00000217407,OTTHUMP00000217408,OTTHUMP00000217423,OTTHUMP00000217424,OTTHUMP00000217562,OTTHUMP00000217563,OTTHUMP00000217584,OTTHUMP00000217585,OTTHUMP00000217586,OTTHUMP00000217587,OTTHUMP00000217609,OTTHUMP00000217610,OTTHUMP00000217611,OTTHUMP00000217622,OTTHUMP00000217623,OTTHUMP00000217625,OTTHUMP00000217627,OTTHUMP00000217628,OTTHUMP00000217638
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human CLDND1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3