Background:Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neurons to regulate the cytoarchitecture of these cells. Analogous to cyclins, the regulatory subunits p35 and p39 associate with and activate CDK5 despite the lack of sequence homology.
仕様
Synonyms:Cdk 5,Cdk5,CDK5,Cell division protein kinase 5,Crk6,Cyclin dependent kinase 5,Cyclin-dependent kinase 5,Protein kinase CDK5 splicing,PSSALRE,Serine threonine protein kinase PSSALRE,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human CDK5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:25-1:100
Swissprot:Q00535
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Neuroscience