Background：This gene encodes a member of the bone morphogenetic protein （BMP） receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine （threonine） kinase receptors： type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
仕様
Synonyms：Activin receptor like kinase 6,Acvrlk6,ALK 6,ALK6,alk6tr,BMP type-1B receptor,BMPR IB,BMPR-1B,Bmpr1b,BMPRIB,BMR1B,Bone morphogenetic protein receptor type 1B,Bone morphogenetic protein receptor type IB,Bone morphogenetic protein receptor type-1B,BR 1b,BR1b,CDw 293,CDw293,CDw293 antigen,CFK 43a,CFK43a,Serine/threonine receptor kinase,zALK 6,zALK6
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human BMPR1B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：O00238
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
