Background：This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus （HIV-1） coreceptor. Two transcript variants resulting from alternative splicing have been identified.
仕様
Synonyms：AGTR L1,AGTRL 1,AGTRL1,Angiotensin II receptor like 1,Angiotensin receptor like 1,Angiotensin receptor-like 1,Apelin receptor,APJ （apelin） receptor,APJ,APJ receptor,APJ,APJR,APLNR,B78,FLJ90771,G protein coupled receptor APJ,G-protein coupled receptor APJ,G-protein coupled receptor HG11,GPCR34,HG 11,HG11,HG11 orphan receptor,MGC45246,MSR,msr/apj
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human APLNR
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P35414
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
