Background：The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA（Ala） in a two-step reaction： alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA（Ala）. Also edits incorrectly charged tRNA（Ala） via its editing domain
