Background:The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:CD218 antigen-like family member A,CD218a,CDw218a,CDw218a antigen,IL 1Rrp,IL-18R-1,IL-18R1,IL-1Rrp,IL1 receptor related protein,IL1 receptor-related protein,IL18R,IL18R1,IL18RA,Il18ralpha,IL1R-rp,IL1RRP,Interleukin 18 receptor 1,Interleukin 18 receptor,alpha chain,Interleukin-18 receptor 1
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Recombinant protein of human IL18R1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3