Background：The protein encoded by this gene is a member of the Toll-like receptor （TLR） family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns （PAMPs） that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
仕様
Synonyms：CD282,CD282 antigen,TIL 4,TIL4,TLR 2,TLR2,TLR2,Toll like receptor 2,Toll like receptor 2 precursor,Toll-like receptor 2,Toll/interleukin 1 receptor like 4,Toll/interleukin 1 receptor like protein 4,Toll/interleukin receptor like protein 4,Toll/interleukin-1 receptor-like protein 4
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human TLR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：O60603
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Microbiology, Signal transduction
