Background：This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
仕様
Synonyms：ADR,AKR1B 1,Akr1b1,Aldehyde reductase 1,Aldehyde reductase,Aldo keto reductase family 1,member B1,Aldo-keto reductase family 1 member B1,aldo-keto reductase family 1,member B1 （aldose reductase）,Aldose reductase,aldr 1,ALDR,aldr1,ALR2,AR,Lii5 2 CTCL tumor antigen,Low Km aldose reductase,MGC1804
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human AKR1B1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P15121
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
