Background：This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.COQ8A （Coenzyme Q8A） is a Protein Coding gene. Diseases associated with COQ8A include Coenzyme Q10 Deficiency, Primary, 4 and Coq8a-Related Coenzyme Q10 Deficiency. An important paralog of this gene is COQ8B.
仕様
Synonyms：aarF domain containing protein kinase 3,aarF domain-containing protein kinase 3,ADCK 3,Adck3,ADCK3,ARCA2,CABC 1,CABC1,Chaperone ABC1 （activity of bc1 complex S.pombe） like,Chaperone ABC1 activity of bc1 complex homolog,Chaperone ABC1 like,Chaperone activity of bc1 complex like,Chaperone activity of bc1 complex like mitochondrial,Chaperone activity of bc1 complex-like,Chaperone-ABC1-like,Coenzyme Q8 homolog,COQ 8,COQ10D4,COQ8,COQ8,S. cerevisiae,homolog of,MGC4849,mitochondrial,OTTHUMP00000035734,OTTHUMP00000035737,SCAR9
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human CABC1.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 50％ glycerol and 0.5％ BSA
Dilution：WB 1：500-1：2000, IHC 1：50-1：200, IF 1：50-1：100, ELISA 1：5000-1：20000
Gene_ID（human）：56997
Swissprot：Q8NI60
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
