Background：This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.
仕様
Synonyms：EAA2,EAAT2,Excitatory amino acid transporter 2,Excitotoxic amino acid transporter 2,Glial high affinity glutamate transporter,GLT 1,GLT1,Glutamate aspartate transporter II,Glutamate transporter 1,Glutamate/aspartate transporter II,Slc1a2,Sodium dependent glutamate aspartate transporter 2,Sodium-dependent glutamate/aspartate transporter 2,solute carrier family 1 （glial high affinity glutamate transporter）,member 2,Solute carrier family 1 glial high affinity glutamate transporter member 2,Solute carrier family 1 member 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/mL
Immunogen：Synthetic Peptide
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：WB 1：1000-2000
Gene_ID（human）：6506
Swissprot：P43004
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
