Background：In mammals, there are several identified isoforms of p21 Activated Protein Kinases or PAKs： PAK1 and PAK3 are mostly brain specific, while PAK2 is expressed ubiquitously. Mutations of the gene coding for PAK3 are associated with X linked mental retardation and PAK3 is a key regulator of synapse formation and plasticity in the hippocampus. PAK3 is thought to play a key role in regulation of cell shape and motility as well as cell death.
仕様
Synonyms：PAK1,Serine/threonine-protein kinase PAK 1,Alpha-PAK,p21-activated kinase 1,PAK-1,p65-PAK,PAK2,Serine/threonine-protein kinase PAK 2,Gamma-PAK,PAK65,S6/H4 kinase,p21-activated kinase 2,PAK-2,p58,PAK3,OPHN3,Serine/threonine-p
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human PAKa/b/gamma around the non-phosphorylation site of T423/402/421.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
