Background:This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signaling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. CBLN4 (Cerebellin 4 Precursor) is a Protein Coding gene. An important paralog of this gene is CBLN2.