Background:Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
仕様
Synonyms:Activating transcription factor 2,Activating transcription factor 2 splice variant ATF2 var2,ATF 2,Atf-2,Atf2,ATF2 protein,ATF2,cAMP Response Element Binding Protein 2,cAMP response element binding protein CRE BP1,cAMP response element-binding protein CRE-BP1,cAMP responsive element binding protein 2,formerly,cAMP-dependent transcription factor ATF-2,cAMP-responsive element-binding protein 2,CRE BP1,CRE-BP,CREB 2,CREB-2,CREB2,CREBP1,Cyclic AMP dependent transcription factor ATF 2,Cyclic AMP-dependent transcription factor ATF-2,Cyclic AMP-responsive element-binding protein 2,D130078H02Rik,D18875,HB 16,HB16,Histone acetyltransferase ATF2,MGC105211,MGC105222,MGC111558,MGC142504,mXBP,MXBP protein,Tg(Gzma-Klra1)7Wum,TREB 7,TREB7
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IP,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human ATF-2 around the non-phosphorylation site of S62.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IP 1:200-1:500, ELISA 1:10000
Gene_ID(human):1386
Swissprot:P15336
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology