Background：The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
仕様
Synonyms：Adapter protein containing PH domain,Adaptor Protein Containing pH Domain,Adaptor protein containing pH domain PTB domain and leucine zipper motif 1,Adaptor protein containing pH domain PTB domain and leucine zipper motif,Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1,AKT2 INTERACTOR,APPL 1,Appl1,DCC interacting protein 13 alpha,DCC-interacting protein 13-alpha,DIP 13 alpha,DIP13 alpha,Dip13-alpha,DIP13alpha,DP13A,KIAA1428,PTB domain and leucine zipper motif 1,PTB Domain and Leucine Zipper Motif,Signaling adaptor protein DIP13alpha
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human APPL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：WB 1：500-1：2000, ELISA 1：40000
Gene_ID（human）：26060
Swissprot：Q9UKG1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Developmental biology, Neuroscience, Signal transduction
