Background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
仕様
Synonyms:14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14 3 3 tau,14 3 3 theta,14-3-3 protein T-cell,14-3-3 protein tau,14-3-3 protein theta,1433T,1C5,HS1,KCIP1,Protein HS1,Protein kinase C inhibitor protein 1,Protein tau,tyr3/trp5 monooxygenase activation protein,theta,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,theta polypeptide,Ywhaq
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human 14-3-3 theta/τ around the non-phosphorylation site of S232.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Gene_ID(human):10971
Swissprot:P27348
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells