Background:Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
仕様
Synonyms:AI325008,BAD,BAD,BBC 2,BBC2,BBC6,Bcl 2 Antagonist of Cell Death,Bcl 2 Binding Component 6,BCL X / BCL 2 Binding Protein,BCL X Binding Protein,Bcl XL/Bcl 2 Associated Death Promoter,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,BCL2 antagonist of cell death protein,BCL2 associated agonist of cell death,Bcl2 Associated Death Promoter,BCL2 binding component 6,BCL2 binding protein,Bcl2 Like 8 Protein,Bcl2-L-8,BCL2L8,Proapoptotic BH3 Only Protein
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of mouse Bad
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.