86-4067-76 ［取扱停止］Rabbit anti-PERK Polyclonal Antibody 20uL RD72747A
[Reddot Biotech] Rabbit anti-PERK Polyclonal Antibody 20uL
特徴
Background：Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 （EIF2）, leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response （UPR）-induced G1 growth arrest due to the loss of cyclin D1.
仕様
Synonyms：DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human PERK around the non-phosphorylation site of Thr981.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：IHC 1：100-1：300, IF 1：50-1：200, ELISA 1：40000
Gene_ID（human）：9451
Swissprot：Q9NZJ5
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism
サイズ：20uL
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