Background:This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
仕様
Synonyms:AAG6,Aging associated gene 6,aPKC,KPCA,PKC alpha,PKC-A,PKC-alpha,PKCA,PRKACA,PRKCA,Protein Kinase C alpha,Protein kinase C alpha type
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human PKC a around the non-phosphorylation site of Thr638.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4