Background：Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
仕様
Synonyms：DBCN,Dbct,DC,DCX,DCX,Doublecortex,Doublin,FLJ51296,Lis X,Lis-X,Lissencephalin X,Lissencephalin-X,Lissencephaly X linked,Lissencephaly X linked doublecortin,LISX,Neuronal migration protein doublecortin,OTTHUMP00000023859,OTTHUMP00000023860,OTTHUMP00000216315,OTTHUMP00000216316,SCLH,XLIS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Doublecortin around the non-phosphorylation site of Ser378.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
