Background：Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
仕様
Synonyms：AI627006,APG4 autophagy 4 homolog A,Apg4a,ATG4 autophagy related 4 homolog A （S. cerevisiae）,ATG4 autophagy related 4 homolog A,ATG4A,ATG4A,Atg4al,AUT like 2 cysteine endopeptidase,AUT-like 2 cysteine endopeptidase,Autl2,Autophagin 2,Autophagin-2,Autophagy related 4A cysteine peptidase,Autophagy related cysteine endopeptidase 2,Autophagy related protein 4 homolog A,Autophagy-related cysteine endopeptidase 2,Autophagy-related protein 4 homolog A,AV169859,Cysteine protease ATG4A,hAPG4A,MGC107179
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human Atg4A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：20000
Gene_ID（human）：115201
Swissprot：Q8WYN0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
