Background：Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue （BAT） differentiation.
仕様
Synonyms：AGP/EBP,C EBP beta,C/EBP beta,C/EBP related protein 2,CCAAT Enhancer Binding Protein beta,CCAAT/enhancer-binding protein beta,CEBPB,CEBPB,CRP2,IL 6DBP,IL6DBP,Interleukin 6 dependent binding protein,LAP,Liver activator protein,Liver enriched transcriptional activator,NF IL6,NFIL6,Nuclear factor NF IL6,Nuclear factor NF-IL6,SF B,SFB,Silencer factor B,TCF-5,TCF5,Transcription factor 5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human C/EBP b around the non-phosphorylation site of Thr235.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：50-1：200, ELISA 1：10000
Gene_ID（human）：1051
Swissprot：P17676
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling
