Background:The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.
仕様
Synonyms:CD49 antigen-like family member E,CD49e,Fibronectin receptor subunit alpha,Fibronectin receptor,alpha subunit,FNRA,Integrin alpha 5 (fibronectin receptor alpha),Integrin alpha-5,Integrin alpha-5 light chain,Integrin alpha-F,Integrin,alpha 5 (fibronectin receptor,alpha polypeptide),ITA5,Itga5,Very late activation protein 5,alpha subunit,VLA-5,VLA5,VLA5A
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of human Integrin a5.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4