Background：Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3.
仕様
Synonyms：AIS,ANDR,Androgen nuclear receptor variant 2,Androgen receptor （dihydrotestosterone receptor,testicular feminization,spinal and bulbar muscular atrophy,Kennedy disease）,Androgen receptor,androgen receptor splice variant 4b,AR,AR8,DHTR,Dihydro testosterone receptor,Dihydrotestosterone receptor （DHTR）,Dihydrotestosterone receptor,HUMARA,HYSP1,KD,Kennedy disease （KD）,NR3C4,Nuclear receptor subfamily 3 group C member 4 （NR3C4）,Nuclear receptor subfamily 3 group C member 4,SBMA,SMAX1,Spinal and bulbar muscular atrophy （SBMA）,Spinal and bulbar muscular atrophy,Testicular Feminization （TFM）,TFM
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human AR.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-2000, IHC 1：50-300, IF 1：50-1：200, ELISA 1：10000-20000
Gene_ID（human）：367
Swissprot：P10275
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction
