Background:The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:c14_5527,C14orf41,FLJ31314,h Numb,h-Numb,Numb,Numb homolog (Drosophila),Numb homolog,Numb protein homolog,NUMB,Protein numb homolog,Protein S171,S171
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of human NUMB.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4