Background：Serine/threonine-protein kinase PLK1, also known aspolo-like kinase 1（PLK-1） orserine/threonine-protein kinase 13（STPK13）, is anenzymethat in humans is encoded by thePLK1（polo-like kinase1）gene. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
仕様
Synonyms：Cell cycle regulated protein kinase,PLK 1,PLK,PLK-1,plk1,PLK1,Polo like kinase 1,Polo-like kinase 1,Serine/threonine protein kinase 13,Serine/threonine protein kinase PLK1,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase PLK1,STPK 13,STPK13
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Plk1 around the non-phosphorylation site of Ser137.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：20000
Gene_ID（human）：5347
Swissprot：P53350
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
