Background:This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms:65 kDa Yes associated protein,65 kDa Yes-associated protein,COB1,YAp 1,YAP 65,YAP,YAP1,YAP1,YAP2,YAP65,yes -associated protein delta,Yes associated protein 1 65kDa,Yes associated protein 1,Yes associated protein 2,yes associated protein beta,YKI,Yorkie homolog
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human YAP around the non-phosphorylation site of Ser127.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4