Background：This gene encodes a protein that is a member of the SUMO （small ubiquitin-like modifier） protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
仕様
Synonyms：DAP1,GAP modifying protein 1,GAP-modifying protein 1,GMP 1,GMP1,OFC10,PIC 1,PIC1,SENP2,Sentrin 1,Sentrin,Small ubiquitin related modifier 1,Small ubiquitin-like modifier 1,Small ubiquitin-related modifier 1,SMT3,SMT3 homolog 3,SMT3 suppressor of mif two 3 homolog 1,SMT3,yeast,homolog 3,Smt3C,SMT3H3,SUMO-1,SUMO1,SUMO1,Ubiquitin homology domain protein PIC1,Ubiquitin Like 1,Ubiquitin like protein SMT3C,Ubiquitin like protein UBL1,Ubiquitin-homology domain protein PIC1,Ubiquitin-like protein SMT3C,Ubiquitin-like protein UBL1,UBL 1,UBL1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the N-terminal region of human SUMO-1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：20000
Gene_ID（human）：7341
Swissprot：P63165
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism
