Background：The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone （AMH） gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
仕様
Synonyms：campomelic dysplasia autosomal sex reversal,CMD 1,CMD1,CMPD 1,CMPD1,SOX 9,Sox9,SOX9,SRA 1,SRA1,SRXX2,SRXY10,SRY （sex determining region Y） box 9 （campomelic dysplasia autosomal,SRY （sex determining region Y） box 9,SRY （sex determining region Y）-box 9,SRY （sex-determining region Y）-box 9 protein,SRY related HMG box gene 9,Transcription factor SOX 9,Transcription factor SOX-9,transcription factor SOX9
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Sox-9 around the non-phosphorylation site of Ser181.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：5000
Gene_ID（human）：6662
Swissprot：P48436
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience, Stem cells
