Background：SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS （Elongin BC-CUL2/5-SOCS-box protein） E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
仕様
Synonyms：CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human SOCS-2.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：10000
Gene_ID（human）：8835
Swissprot：O14508
Isotype：IgG
Research Areas：Cancer, Immunology, Neuroscience, Signal transduction
