Background：SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs, common-mediator SMAD and inhibitory SMADs. SMAD1, SMAD5 and SMAD9 have high degrees of homology. SMAD8 and SMAD9 are used as alternate names for the same protein. Human SMAD1 is a 465 amino acid protein, human SMAD5 is a 465 amino acid and human SMAD9 is a 430 amino acid protein.
仕様
Synonyms：SMAD1,BSP1,MADH1,MADR1,Mothers against decapentaplegic homolog 1,MAD homolog 1,Mothers against DPP homolog 1,JV4-1,Mad-related protein 1,SMAD family member 1,SMAD 1,Smad1,hSMAD1,Transforming growth factor-beta-signaling protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the N-terminal region of human Smad1/5/9
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：50-1：200, ELISA 1：10000
Gene_ID（human）：4086/4090/4093
Swissprot：Q15797,Q99717,O15198
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
