Background：Essential component of the SCF （SKP1-CUL1-F-box protein） ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF（BTRC） mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF（Cyclin F） directs ubiquitination of CP110.
仕様
Synonyms：Cyclin A/CDK2 associated p19,Cyclin A/CDK2 associated protein p19,Cyclin-A/CDK2-associated protein p19,EMC19,MGC34403,OCP 2,OCP II,OCP II protein,OCP-2,OCP-II,OCP2,OCPII,Organ of Corti protein 2,Organ of Corti protein II,OTTHUMP00000159379,OTTHUMP00000159380,OTTHUMP00000228275,OTTHUMP00000228276,OTTHUMP00000228278,OTTHUMP00000228279,OTTHUMP00000228281,p19A,p19skp1,RNA polymerase II elongation factor like protein,RNA polymerase II elongation factor like protein OCP2,RNA polymerase II elongation factor-like protein,S phase kinase associated protein 1,S phase kinase associated protein 1A,S phase kinase associated protein 1A p19A,S-phase kinase-associated protein 1,SIII,Skp 1,SKP 1A,skp1,SKP1,SKP1A,TCEB1L,Transcription Elongation Factor B 1 like,Transcription elongation factor B,Transcription elongation factor B SIII polypeptide 1 like
Host：Rabbit
Reactivity：Human,Mouse,Rat,Monkey
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human Skp1 p19
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
