Background:This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.PTPRZ1 (Protein Tyrosine Phosphatase, Receptor Type Z1) is a Protein Coding gene. Diseases associated with PTPRZ1 include H. Pylori Infection and Hyperlysinemia. Among its related pathways are Spinal Cord Injury and Insulin receptor recycling. GO annotations related to this gene include phosphatase activity and transmembrane receptor protein tyrosine phosphatase activity. An important paralog of this gene is PTPRG.
仕様
Synonyms:3F8 chondroitin sulfate proteoglycan,3H1 keratan sulfate proteoglycan,HPTPZ,HPTPzeta,Phosphacan,Protein tyrosine phosphatase receptor type Z polypeptide 2,Protein tyrosine phosphatase,receptor type,Z polypeptide 1,Protein tyrosine phosphatase,receptor type,zeta polypeptide 1,Protein-tyrosine phosphatase receptor type Z polypeptide 1,Protein-tyrosine phosphatase receptor type Z polypeptide 2,PTP-ZETA,PTP18,PTPRZ,PTPRZ,Ptprz1,PTPZ,R PTP zeta 2,R-PTP-zeta,R-PTP-zeta-2,Receptor type tyrosine phosphatase beta/zeta,Receptor-type tyrosine-protein phosphatase zeta,RPTP-BETA,RPTPB,RPTPbeta
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the N-terminal region of human PTPζ
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, ELISA 1:5000
Gene_ID(human):5803
Swissprot:P23471
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction