Background：This gene encodes a member of the peroxisome proliferator-activated receptor （PPAR） subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors （RXRs） and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known： PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
仕様
Synonyms：CIMT1,GLM1,NR1C3,Nuclear receptor subfamily 1 group C member 3,OTTHUMP00000185032,OTTHUMP00000185036,Peroxisome proliferator activated nuclear receptor gamma variant 1,Peroxisome proliferator activated receptor gamma 1,Peroxisome Proliferator Activated Receptor gamma,Peroxisome proliferator-activated receptor gamma,PPAR gamma,PPAR-gamma,PPARG,PPARG,PPARG1,PPARG2,PPARgamma
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human PPAR-gamma around the non-phosphorylation site of Ser112.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：50-1：200, ELISA 1：10000
Gene_ID（human）：5468
Swissprot：P37231
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Stem cells
