Background:This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
仕様
Synonyms:CVID9,D14Ertd420e,Kinase PKC delta,KPCD,KPCD,MAY 1,MAY1,MGC49908,nPKC delta,nPKC-delta,PCKd,PKC d,PKC delta,PKCD,PKCdelta,PRKC D,PRKC delta,Prkcd,Protein Kinase C delta,Protein kinase C delta type,Protein kinase C delta VIII,Protein Kinase Cdelta,Tyrosine protein kinase PRKCD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human PKC delta around the non-phosphorylation site of Thr507.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4