Background：Functions as an E3-type small ubiquitin-like modifier （SUMO） ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
仕様
Synonyms：E3 SUMO protein ligase PIAS 3,E3 SUMO protein ligase PIAS3,E3 SUMO-protein ligase PIAS3,FLJ14651,OTTHUMP00000015586,OTTHUMP00000015587,PIAS 3,Pias3,PIAS3 protein,PIAS3,Protein inhibitor of activated STAT 3,Protein inhibitor of activated STAT protein 3,Protein inhibitor of activated STAT3,Zinc finger MIZ type containing 5,ZMIZ 5,ZMIZ5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the N-terminal region of human PIAS 3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
