Background：The PFKP gene encodes the platelet isoform of phosphofructokinase （PFK） （ATP：D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11）. PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle （PFKM; MIM 610681） and liver （PFKL; MIM 171860） isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora （1981） [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2
仕様
Synonyms：1200015H23Rik,6 phosphofructokinase type C,6 phosphofructokinase,platelet type,6-phosphofructokinase,6-phosphofructokinase type C,9330125N24Rik,FLJ40226,K6PP,K6PP,MGC105718,PFK C,PFK,fibroblast type,PFK-C,PFKF,PFKP,Phosphofructo 1 kinase isozyme C,Phosphofructo-1-kinase isozyme C,Phosphofructokinase 1,Phosphofructokinase platelet,Phosphohexokinase,platelet type
Host：Rabbit
Reactivity：Human,Mouse,Rat,Monkey
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human PFK-C
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：5000
Gene_ID（human）：5214
Swissprot：Q01813
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
