Background:This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
仕様
Synonyms:Octamer binding transcription factor 4,MGC22487,Oct 3,Oct 4,Oct-3,Oct-4,OCT3,Oct4,Octamer binding protein 3,Octamer binding protein 4,Octamer binding transcription factor 3,Octamer-binding protein 3,Octamer-binding protein 4,Octamer-binding transcription factor 3,OTF 3,OTF 4,OTF-3,OTF3,OTF4,PO5F1,POU class 5 homeobox 1,POU domain class 5 transcription factor 1,POU domain transcription factor OCT4,POU domain,class 5,transcription factor 1,POU-type homeodomain-containing DNA-binding protein,POU5F1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of human Oct-3/4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4