Background：NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. P52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human NFKB2.
仕様
Synonyms：CVID10,DNA binding factor KBF2,H2TF1,Lymphocyte translocation chromosome 10 protein,LYT 10,NF kB2,NFKB p52/p100 subunit,Nuclear factor Kappa B subunit 2,Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 （p49/p100）,Nuclear factor of kappa light polypeptide gene enhancer in B cells 2,Oncogene Lyt 10,p100,Transcription factor NFKB2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,IP,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human NFkappaB-p100 around the non-phosphorylation site of Ser865.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, IP 1：200-1：500, ELISA 1：20000
Gene_ID（human）：4791
Swissprot：Q00653
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
