Background：This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.CDC42BPB （CDC42 Binding Protein Kinase Beta） is a Protein Coding gene. Diseases associated with CDC42BPB include Myotonic Dystrophy and Lung Large Cell Carcinoma. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDC42BPA.
仕様
Synonyms：CDC42 binding protein kinase beta,CDC42-binding protein kinase beta,CDC42BPB,DMPK like beta,DMPK-like beta,KIAA1124,MRCK beta,MRCKB,Myotonic dystrophy kinase related CDC42 binding kinase beta,Myotonic dystrophy kinase-related CDC42-binding kinase beta,Myotonic dystrophy protein kinase like beta,Myotonic dystrophy protein kinase-like beta,Serine/threonine protein kinase MRCK beta,Serine/threonine-protein kinase MRCK beta
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the C-terminal region of human MRCKb
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
