Background:The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
仕様
Synonyms:antigen identified by monoclonal L230,CD 51,CD51,DKFZp686A08142,Integrin alpha five,integrin alpha V beta 3,Integrin alpha-5,integrin alpha-V,Integrin alpha-V light chain,integrin alphaVbeta3,integrin,alpha V (vitronectin receptor,alpha polypeptide,antigen CD51),ITAV,ITGAV,MSK 8,Msk8,Vitronectin receptor subunit alpha,VNRA,VTNR
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of human Integrin aV.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4