Background:Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
仕様
Synonyms:I kappa B kinase 2,I kappa B kinase beta,I-kappa-B kinase 2,I-kappa-B-kinase beta,IkBKB,IKK beta,IKK-B,IKK-beta,IKK2,IKKB,IKKB,IMD15,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase beta,Inhibitor of nuclear factor kappa-B kinase subunit beta,NFKBIKB,Nuclear factor NF-kappa-B inhibitor kinase beta
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human IKKb around the non-phosphorylation site of Tyr188.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4