Background：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC5 （Histone Deacetylase 5） is a Protein Coding gene. Diseases associated with HDAC5 include Polycystic Kidney Disease, Adult Type I. Among its related pathways are PEDF Induced Signaling and Phospholipase-C Pathway. GO annotations related to this gene include transcription factor binding and transcription corepressor activity. An important paralog of this gene is HDAC4. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 （Histone Deacetylase 9） is a Protein Coding gene. Diseases associated with HDAC9 include Gastrointestinal Neuroendocrine Tumor and Cutaneous T Cell Lymphoma. Among its related pathways are PEDF Induced Signaling and Phospholipase-C Pathway. GO annotations related to this gene include transcription factor binding and histone deacetylase binding. An important paralog of this gene is HDAC5.
